The Hilarious World of Depression Podcast

A show about clinical depression…with laughs? Well, yeah. Depression is an incredibly common and isolating disease experienced by millions, yet often stigmatized by society. The Hilarious World of Depression is a series of frank, moving, and, yes, funny conversations with people who have dealt with this disease, hosted by veteran humorist and public radio host John Moe. Please visit the American Public Media website to learn more and listen to additional episodes of the podcast.

Jenny Lawson is Very Fond of Creepy Smiling Dead Animals and Worries Quite a Bit

She’s the author of bestselling books and an incredibly popular blog, but Jenny Lawson showed up to our interview wondering, at least a little, if her appearance on this show and her whole career, really, was part of some delusion. It’s not. She’s the real thing: an incredibly funny and honest writer with a legion of fans, a very old decapitated and stuffed boar’s head named James Garfield, anxiety, depression, and a clear-eyed view of the world.

Previous Episodes

She’s the author of bestselling books and an incredibly popular blog, but Jenny Lawson showed up to our interview wondering, at least a little, if her appearance on this show and her whole career, really, was part of some delusion. It’s not. She’s the real thing: an incredibly funny and honest writer with a legion of fans, a very…

We’ve gathered up a whole lot of tips, tricks, ideas, and stories to help you get through this time of year when merriness and jolliness aren’t always in abundant supply. Hear holiday thoughts from Wil Wheaton, Margaret Cho, Jenny Lawson, John Green, Aimee Mann, and more. Plus, a story about a slobbering zebra.

You know those things that happened but that you don’t talk about very much? Or even at all? Because they’re too upsetting? In this episode, host John Moe and guest Ana Marie Cox put those things on the table. Ana is a journalist, pundit, and podcaster; she talks about the lowest point in her mental health, a horrible decision,…

Growing up, actor and writer Julie Klausner was too busy battling depression and daydreaming about an imagined Merlot-sipping cosmopolitan adulthood to really engage in the world itself. It wasn’t until she entered the world of comedy and improv as an adult that things really started to click into place. That led to creating Difficult People, a show on Hulu,…

Long before Jeff Tweedy was the founder and leader of the enormously popular band Wilco, he was a kid in Illinois with severe migraines and a tendency toward anxiety and depression. He cycled through alcohol, marijuana, and, finally, opioids to try to get to the point of feeling normal and okay, even relying on a fan who worked at…

With one recent appearance on The Tonight Show, Patti Harrison went from being a well-regarded alternative comedian in New York to being a de facto spokesperson for transgender people. She’s proud of who she is and proud to give a voice to that community. But she wants to make it clear that her sense of humor is much darker,…

Although Gary Gulman has been a successful stand-up comedian for decades – with acclaimed specials, a loyal fan base, and appearances on all major late night shows – this was not his original plan. Gary is 6’6” and athletically gifted, he loved basketball, and had a full ride athletic scholarship to a Division 1 program. Problem is, he had…

Singer/songwriter Aimee Mann has a reputation for making music that is raw, emotional, and sometimes not all that cheerful. In real life, she’s perfectly cheerful – thank you very much – and has traveled a long road of depression, anxiety, a difficult childhood, and writer’s block. Through it all, she’s taken a calm, considered, and creative approach to problem-solving…

Author John Green had one of the best-selling books of the last 10 years with The Fault In Our Stars. The problem is, when you write an acclaimed smash hit, everyone wants you to somehow do it again. In attempting to write that follow-up, Green went off the meds he’d been taking for Obsessive-Compulsive Disorder, hoping it would bring him…

If you’ve enjoyed any comedy in the last 20 years, there’s a good chance Neal Brennan helped make it. He’s a veteran comic, writer, director, and co-creator, with Dave Chappelle, of the acclaimed Chappelle’s Show. Over the past 20-plus years, he’s also tried everything he could think of to tame his depression. Hear Neal’s epic journey to feeling pretty good.

She’s one of the most influential and innovative comedians of the last few decades, but before all that, Margaret Cho was a Korean-American girl growing up in the 1970s in San Francisco. We hear about the sometimes very darkly humorous ways her family and culture dealt with depression and suicide, and how she harnessed her own depression to begin…

Wil Wheaton was a child star in Stand By Me, a regular on Star Trek: The Next Generation as a teenager, and has been trying to figure out his role in show business for a long time since then. He was dealing with the pressures of fame and the fickle tastes of Hollywood, all while dealing with a chemical imbalance in his…

Hosted by John Moe
John Moe is the author of three books: Dear Luke, We Need To Talk, Darth; The Deleted Emails Of Hillary Clinton; and Conservatize Me. His writing has appeared in numerous humor anthologies as well as The New York Times Magazine, The Seattle Times, MSN, and many more publications. He has hosted nationally dis tributed public radio programs such as Wits, Weekend America, and Marketplace Tech Report and his radio work has been featured on All Things Considered and Morning Edition. He is also the host and creator of the award winning podcast The Hilarious World of Depression. Locally, he can be heard on MPR News and The Current. He lives in St Paul.